Adherens Junctions: from Molecular Mechanisms to Tissue - download pdf or read online

By Tony J. C. Harris (auth.), Tony Harris (eds.)

ISBN-10: 9400741855

ISBN-13: 9789400741850

ISBN-10: 9400741863

ISBN-13: 9789400741867

Cell–cell adhesion is prime for the improvement and homeostasis of animal tissues and organs. Adherens junctions (AJs) are the simplest understood cell-cell adhesion complexes. during this quantity, a bunch of across the world famous specialists studies AJ biology over quite a lot of association; from atoms to molecules, to protein complexes, molecular networks, cells, tissues, and total animal improvement. AJs have additionally been an essential component of animal evolution, and play principal roles in melanoma improvement, pathogen an infection and different ailments. This e-book addresses significant questions encompassing AJ biology.
• How did AJs evolve?
• How do cadherins and catenins have interaction to collect AJs and mediate adhesion?
• How do AJs interface with different mobile equipment to couple adhesion with the total telephone?
• How do AJs impact phone behaviour and multicellular improvement?
• How can irregular AJ task result in disease?

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Additional info for Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease

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011 Sakarya O, Armstrong KA, Adamska M, Adamski M, Wang IF, Tidor B, Degnan BM, Oakley TH, Kosik KS (2007) A post-synaptic scaffold at the origin of the animal kingdom. PLoS ONE 2(6):e506. 0000506 Salomon D, Ayalon O, Patel-King R, Hynes RO, Geiger B (1992) Extrajunctional distribution of N-cadherin in cultured human endothelial cells. J Cell Sci 102:7–17 Sasakura Y, Shoguchi E, Takatori N, Wada S, Meinertzhagen IA, Satou Y, Satoh N (2003) A genomewide survey of developmentally relevant genes in Ciona intestinalis.

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Nature 421:543–547. 1038/nature01366 Mahoney PA, Weber U, Onofrechuk P, Biessmann H, Bryant PJ, Goodman CS (1991) The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily. Cell 67:853–868. 1016/0092-8674(91)90359-7 Mariner DJ, Wang J, Reynolds AB (2000) ARVCF localizes to the nucleus and adherens junction and is mutually exclusive with p120ctn in E-cadherin complexes. J Cell Sci 113:1481– 1490 Matakatsu H, Blair SS (2004) Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing.

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Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease by Tony J. C. Harris (auth.), Tony Harris (eds.)


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